Juan C. Martinez Camarillo MD from USC Roski Eye Institute / USC Institute of Biomedical Therapeutics, Los Angeles, CA, USA going to give talk at Pediatric Ophthalmology 2018.
Optical coherence tomography (OCT) is a non-invasive, interferometric imaging modality that enables cross-section imaging of the retina introduced in 1991. OCT Angiography (OCTA), initially described in 2005 and used in human eyes with methods based on amplitude or intensity until 2012. OCTA analyze in vivo structural and function of the retinal vasculature. A systematic review from advantages, disadvantages, results and expectations about OCTA in pediatric patients was addressed in this work. OCTA, an imaging technology dye-free open the possibility to increase its use in the entire range of pediatric patients without the side effects related to fluorescein and indocyanine green dyes. As described previously in many publications, scanning methodology used to generate the motion contrast signal, data processing, movement of the eye, and intrinsic properties of the eye are the well-known OCTA artefacts. Eye movement and intrinsic properties of the eye play an important role in children, due to eye development and its constant changes. The majority of the previous studies about OCTA in healthy patients were related to adults, likewise clinical studies using OCTA, such as diabetic retinopathy, retinal occlusions, age-related macular degeneration and macular edema secondary to uveitis. After an extensive review in publication about pediatric patients, limited data from healthy children has been published. Furthermore, only case series and case control studies have been published including amblyopia and retinopathy of prematurity. Cases reports and case series are the only data available so far. Near future includes portable and intraoperative OCTA devices, being the next generation of imaging acquisition for pediatric patients.
Optical coherence tomography (OCT) is a non-invasive, interferometric imaging modality that enables cross-section imaging of the retina introduced in 1991. OCT Angiography (OCTA), initially described in 2005 and used in human eyes with methods based on amplitude or intensity until 2012. OCTA analyze in vivo structural and function of the retinal vasculature. A systematic review from advantages, disadvantages, results and expectations about OCTA in pediatric patients was addressed in this work. OCTA, an imaging technology dye-free open the possibility to increase its use in the entire range of pediatric patients without the side effects related to fluorescein and indocyanine green dyes. As described previously in many publications, scanning methodology used to generate the motion contrast signal, data processing, movement of the eye, and intrinsic properties of the eye are the well-known OCTA artefacts. Eye movement and intrinsic properties of the eye play an important role in children, due to eye development and its constant changes. The majority of the previous studies about OCTA in healthy patients were related to adults, likewise clinical studies using OCTA, such as diabetic retinopathy, retinal occlusions, age-related macular degeneration and macular edema secondary to uveitis. After an extensive review in publication about pediatric patients, limited data from healthy children has been published. Furthermore, only case series and case control studies have been published including amblyopia and retinopathy of prematurity. Cases reports and case series are the only data available so far. Near future includes portable and intraoperative OCTA devices, being the next generation of imaging acquisition for pediatric patients.